Cargando…

Evaluation of food effects on the pharmacokinetics of Pelargonium sidoides and Coptis with each bioactive compound berberine and epicatechin after a single oral dose of an expectorant and antitussive agent UI026 in healthy subjects

UI026 is an expectorant and antitussive agent which is a new combination of Pelargonium sidoides extract and Coptis extract. The bioactive compounds of Pelargonium sidoides and Coptis extracts were identified as epicatechin and berberine, respectively. This study evaluated the effect of food on the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Yewon, Jung, WonTae, Yang, Eunsol, Nam, Kyu-Yeol, Bong, Woo-Ri, Kim, Jaehee, Kim, Kyu Yeon, Lee, SeungHwan, Cho, Joo-Youn, Hong, Jang-Hee, Kim, JaeWoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Clinical Pharmacology and Therapeutics 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979756/ https://www.ncbi.nlm.nih.gov/pubmed/35419311 http://dx.doi.org/10.12793/tcp.2022.30.e3

Ejemplares similares

Effects of Pelargonium sidoides and Coptis Rhizoma 2 : 1 Mixed Formula (PS + CR) on Ovalbumin-Induced Asthma in Mice
por: Min, Byung Gu, et al.
Publicado: (2020)

Combination of Pelargonium sidoides and Coptis chinensis root inhibits nuclear factor kappa B-mediated inflammatory response in vitro and in vivo
por: Park, Sang Mi, et al.
Publicado: (2018)

Medicinal properties and conservation of Pelargonium sidoides DC.
por: Moyo, Mack, et al.
Publicado: (2014)

Preparation of Naringenin Nanosuspension and Its Antitussive and Expectorant Effects
por: Dong, Zhengqi, et al.
Publicado: (2022)

Expectorant and Antitussive Effect of Hedera helix and Rhizoma coptidis Extracts Mixture
por: Song, Kee Jae, et al.
Publicado: (2015)

Antitussive, expectorant activity of Marsilea minuta L., an Indian vegetable
por: Chakraborty, Raja, et al.
Publicado: (2013)

Antioxidant and antimicrobial properties of Pelargonium sidoides DC and lactoferrin combination
por: Terlizzi, Michela, et al.
Publicado: (2020)

Anti-inflammatory, expectorant, and antitussive properties of Kyeongok-go in ICR mice
por: Hu, Jin-Ryul, et al.
Publicado: (2021)

Inclusion of vitexin in β-cyclodextrin: preparation, characterization and expectorant/antitussive activities
por: Costa, Eliatania Clementino, et al.
Publicado: (2020)

Novel kinase platform for the validation of the anti-tubercular activities of Pelargonium sidoides (Geraniaceae)
por: Lukman, V., et al.
Publicado: (2020)

Yield and Metabolite Production of Pelargonium sidoides DC. in Response to Irrigation and Nitrogen Management
por: Mofokeng, Motiki M., et al.
Publicado: (2020)

In Vivo Evaluation of the Antiasthmatic, Antitussive, and Expectorant Activities and Chemical Components of Three Elaeagnus Leaves
por: Ge, Yuebin, et al.
Publicado: (2015)

Investigation of Antibacterial and Antiinflammatory Activities of Proanthocyanidins from Pelargonium sidoides DC Root Extract
por: Jekabsone, Aiste, et al.
Publicado: (2019)

Antimicrobial, Antiviral and Immunomodulatory Activity Studies of Pelargonium sidoides (EPs(®) 7630) in the Context of Health Promotion
por: Kolodziej, Herbert
Publicado: (2011)

The Root Extract of the Medicinal Plant Pelargonium sidoides Is a Potent HIV-1 Attachment Inhibitor
por: Helfer, Markus, et al.
Publicado: (2014)

Antitussive, expectorant and analgesic effects of the ethanol seed extract of Picralima nitida (Stapf) Th. & H. Durand
por: Dapaah, Gabriel, et al.
Publicado: (2016)

Effects of Pelargonium sidoides extract on chemokine levels in nasal secretions of patients with non-purulent acute rhinosinusitis
por: Perić, Aleksandar, et al.
Publicado: (2020)

Interaction of Pelargonium sidoides Compounds with Lactoferrin and SARS-CoV-2: Insights from Molecular Simulations
por: Iacovelli, Federico, et al.
Publicado: (2022)

Draft Genome Sequence of Bacillus sp. strain YC2, an Isolate from the South African Medicinal Plant Pelargonium sidoides
por: Mqulwa, Aza Z., et al.
Publicado: (2022)

The possible mode of antitussive and expectorant activity of the ethanol seed extracts of Picralima nitida ((Stapf) Th. & H. Durand)
por: Dapaah, Gabriel, et al.
Publicado: (2016)

Study on the Effect of Deep Eutectic Solvent Liquid Phase Microextraction on Quality Standard, Antitussive, and Expectorant of Sangbaipi Decoction
por: Li, Lijing, et al.
Publicado: (2021)

Bioactive Compound Produced by Endophytic Fungi Isolated From Pelargonium sidoides Against Selected Bacteria of Clinical Importance
por: Manganyi, Madira Coutlyne, et al.
Publicado: (2019)

Effects of Pelargonium sidoides extract vs roxithromycin on chemokine levels in nasal secretions of patients with uncomplicated acute rhinosinusitis
por: Perić, Aleksandar, et al.
Publicado: (2020)

Expectorants and Anti-Expectorants
Publicado: (1942)

The Pelargonium sidoides Extract EPs 7630 Drives the Innate Immune Defense by Activating Selected MAP Kinase Pathways in Human Monocytes
por: Witte, Katrin, et al.
Publicado: (2015)

Efficacy of Proanthocyanidins from Pelargonium sidoides Root Extract in Reducing P. gingivalis Viability While Preserving Oral Commensal S. salivarius
por: Savickiene, Nijole, et al.
Publicado: (2018)

Up-Regulated Vitamin D Receptor by Pelargonium sidoides Extract EPs(®) 7630 Contributes to Rhinovirus Defense in Bronchial Epithelial Cells
por: Roth, Michael, et al.
Publicado: (2021)

Discovering the Major Antitussive, Expectorant, and Anti-Inflammatory Bioactive Constituents in Tussilago farfara L. Based on the Spectrum–Effect Relationship Combined with Chemometrics
por: Yang, Liu, et al.
Publicado: (2020)

Corrigendum to: “Inclusion of vitexin in β-cyclodextrin: preparation, characterization and expectorant/antitussive activities” [Heliyon 6 (12) (December 2020) e05461]
por: Costa, Eliatania Clementino, et al.
Publicado: (2021)

Pelargonium sidoides extract EPs 7630: a review of its clinical efficacy and safety for treating acute respiratory tract infections in children
por: Careddu, Domenico, et al.
Publicado: (2018)

Investigation of the influence of EPs(®) 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses
por: Michaelis, Martin, et al.
Publicado: (2011)

Effects of Pelargonium sidoides extract EPs 7630 on acute cough and quality of life – a meta-analysis of randomized, placebo-controlled trials
por: Kardos, Peter, et al.
Publicado: (2022)

Pelargonium sidoides radix extract EPs 7630 reduces rhinovirus infection through modulation of viral binding proteins on human bronchial epithelial cells
por: Roth, Michael, et al.
Publicado: (2019)

Antiviral and Immunomodulatory Effects of Pelargonium sidoides DC. Root Extract EPs® 7630 in SARS-CoV-2-Infected Human Lung Cells
por: Papies, Jan, et al.
Publicado: (2021)

Pelargonium sidoides Root Extract: Simultaneous HPLC Separation, Determination, and Validation of Selected Biomolecules and Evaluation of SARS-CoV-2 Inhibitory Activity
por: Alossaimi, Manal A., et al.
Publicado: (2022)

Expectorant
Publicado: (1893)

Evaluation of pharmacodynamic activities of EPs(®) 7630, a special extract from roots of Pelargonium sidoides, in animals models of cough, secretolytic activity and acute bronchitis
por: Bao, Yanyan, et al.
Publicado: (2015)

Corrigendum: Antiviral and Immunomodulatory Effects of Pelargonium sidoides DC. Root Extract EPs(®) 7630 in SARS-CoV-2-Infected Human Lung Cells
por: Papies, Jan, et al.
Publicado: (2021)

On Expectorated Matter
por: Pearson, George
Publicado: (1810)

On Fetid Expectoration
por: Gamgee, Arthur
Publicado: (1865)

Cannot write session to /tmp/vufind_sessions/sess_hl3132uk65arp4u6t9l1hulj9u