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Zygotic gene activation in mice: profile and regulation

The zygotic genome is transcriptionally silent immediately after fertilization. In mice, initial activation of the zygotic genome occurs in the middle of the one-cell stage. At the mid-to-late two-cell stage, a burst of gene activation occurs after the second round of DNA replication, and the profil...

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Detalles Bibliográficos
Autor principal: AOKI, Fugaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979797/
https://www.ncbi.nlm.nih.gov/pubmed/35034936
http://dx.doi.org/10.1262/jrd.2021-129