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BRCA1 and BRCA2 pathogenic variants and prostate cancer risk: systematic review and meta-analysis

BACKGROUND: BRCA1 and BRCA2 pathogenic variants (PVs) are associated with prostate cancer (PCa) risk, but a wide range of relative risks (RRs) has been reported. METHODS: We systematically searched PubMed, Embase, MEDLINE and Cochrane Library in June 2021 for studies that estimated PCa RRs for male...

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Detalles Bibliográficos
Autores principales: Nyberg, Tommy, Tischkowitz, Marc, Antoniou, Antonis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979955/
https://www.ncbi.nlm.nih.gov/pubmed/34963702
http://dx.doi.org/10.1038/s41416-021-01675-5