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Oxidative stress-induced circKIF18A downregulation impairs MCM7-mediated anti-senescence in intervertebral disc degeneration
Low back pain, triggered by intervertebral disc degeneration (IVDD), is one of the most common causes of disability and financial expenditure worldwide. However, except for surgical interventions, effective medical treatment to prevent the progression of IVDD is lacking. This study aimed to investig...
Autores principales: | Wang, Jianle, Xia, Dongdong, Lin, Yan, Xu, Wenbin, Wu, Yaosen, Chen, Jiaoxiang, Chu, Junjie, Shen, Panyang, Weng, Sheji, Wang, Xiangyang, Shen, Lifeng, Fan, Shunwu, Shen, Shuying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979962/ https://www.ncbi.nlm.nih.gov/pubmed/35332256 http://dx.doi.org/10.1038/s12276-022-00732-0 |
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