GITR/GITRL reverse signalling modulates the proliferation of hepatic progenitor cells by recruiting ANXA2 to phosphorylate ERK1/2 and Akt

Hepatic stem/progenitor cells are the major cell compartment for tissue repair when hepatocyte proliferation is compromised in chronic liver diseases, but the expansion of these cells increases the risk of carcinogenesis. Therefore, it is essential to explore the pathways restricting their expansion...

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Detalles Bibliográficos
Autores principales: He, Yu, Pei, Yufeng, Liu, Kai, Liu, Lin, Tian, Yue, Li, Hongyi, Cong, Min, Liu, Tianhui, Ma, Hong, You, Hong, Jia, Jidong, Zhang, Dong, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979965/
https://www.ncbi.nlm.nih.gov/pubmed/35379781
http://dx.doi.org/10.1038/s41419-022-04759-z

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