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Immunosuppressive niche engineering at the onset of human colorectal cancer
The evolutionary dynamics of tumor initiation remain undetermined, and the interplay between neoplastic cells and the immune system is hypothesized to be critical in transformation. Colorectal cancer (CRC) presents a unique opportunity to study the transition to malignancy as pre-cancers (adenomas)...
Autores principales: | Gatenbee, Chandler D., Baker, Ann-Marie, Schenck, Ryan O., Strobl, Maximilian, West, Jeffrey, Neves, Margarida P., Hasan, Sara Yakub, Lakatos, Eszter, Martinez, Pierre, Cross, William C. H., Jansen, Marnix, Rodriguez-Justo, Manuel, Whelan, Christopher J., Sottoriva, Andrea, Leedham, Simon, Robertson-Tessi, Mark, Graham, Trevor A., Anderson, Alexander R. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979971/ https://www.ncbi.nlm.nih.gov/pubmed/35379804 http://dx.doi.org/10.1038/s41467-022-29027-8 |
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