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The miR-98-3p/JAG1/Notch1 axis mediates the multigenerational inheritance of osteopenia caused by maternal dexamethasone exposure in female rat offspring

As a synthetic glucocorticoid, dexamethasone is widely used to treat potential premature delivery and related diseases. Our previous studies have shown that prenatal dexamethasone exposure (PDE) can cause bone dysplasia and susceptibility to osteoporosis in female rat offspring. However, whether the...

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Detalles Bibliográficos
Autores principales: Han, Hui, Xiao, Hao, Wu, Zhixin, Liu, Liang, Chen, Ming, Gu, Hanwen, Wang, Hui, Chen, Liaobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979986/
https://www.ncbi.nlm.nih.gov/pubmed/35332257
http://dx.doi.org/10.1038/s12276-022-00743-x

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