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Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells

The metabolic principles underlying the differences between follicular and marginal zone B cells (FoB and MZB, respectively) are not well understood. Here we show, by studying mice with B cell-specific ablation of the catalytic subunit of glutamate cysteine ligase (Gclc), that glutathione synthesis...

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Detalles Bibliográficos
Autores principales: Franchina, Davide G., Kurniawan, Henry, Grusdat, Melanie, Binsfeld, Carole, Guerra, Luana, Bonetti, Lynn, Soriano-Baguet, Leticia, Ewen, Anouk, Kobayashi, Takumi, Farinelle, Sophie, Minafra, Anna Rita, Vandamme, Niels, Carpentier, Anaïs, Borgmann, Felix K., Jäger, Christian, Chen, Ying, Kleinewietfeld, Markus, Vasiliou, Vasilis, Mittelbronn, Michel, Hiller, Karsten, Lang, Philipp A., Brenner, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980022/
https://www.ncbi.nlm.nih.gov/pubmed/35379825
http://dx.doi.org/10.1038/s41467-022-29426-x