EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma

Neuroblastoma (NB) accounts for 15% of cancer-related deaths in childhood despite considerable therapeutic improvements. While several risk factors, including MYCN amplification and alterations in RAS and p53 pathway genes, have been defined in NB, the clinical outcome is very variable and difficult...

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Detalles Bibliográficos
Autores principales: Voeltzke, Kai, Scharov, Katerina, Funk, Cornelius Maximilian, Kahler, Alisa, Picard, Daniel, Hauffe, Laura, Orth, Martin F., Remke, Marc, Esposito, Irene, Kirchner, Thomas, Schramm, Alexander, Rotblat, Barak, Grünewald, Thomas G. P., Reifenberger, Guido, Leprivier, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980029/
https://www.ncbi.nlm.nih.gov/pubmed/35379801
http://dx.doi.org/10.1038/s41420-022-00963-0

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