Multilayered control of splicing regulatory networks by DAP3 leads to widespread alternative splicing changes in cancer

The dynamic regulation of alternative splicing requires coordinated participation of multiple RNA binding proteins (RBPs). Aberrant splicing caused by dysregulation of splicing regulatory RBPs is implicated in numerous cancers. Here, we reveal a frequently overexpressed cancer-associated protein, DA...

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Detalles Bibliográficos
Autores principales: Han, Jian, An, Omer, Ren, Xi, Song, Yangyang, Tang, Sze Jing, Shen, Haoqing, Ke, Xinyu, Ng, Vanessa Hui En, Tay, Daryl Jin Tai, Tan, Hui Qing, Kappei, Dennis, Yang, Henry, Chen, Leilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980049/
https://www.ncbi.nlm.nih.gov/pubmed/35379802
http://dx.doi.org/10.1038/s41467-022-29400-7

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