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KLF5 inhibition overcomes oxaliplatin resistance in patient-derived colorectal cancer organoids by restoring apoptotic response

Oxaliplatin resistance is a major challenge in the treatment of colorectal cancer (CRC). Many molecular targeted drugs for refractory CRC have been developed to solve CRC drug resistance, but their effectiveness and roles in the progression of CRC and oxaliplatin resistance remain unclear. Here, we...

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Detalles Bibliográficos
Autores principales:	Shen, Xiaohui, Zhang, Yuchen, Xu, Zhuoqing, Gao, Han, Feng, Wenqing, Li, Wenchang, Miao, Yiming, Xu, Zifeng, Zong, Yaping, Zhao, Jingkun, Lu, Aiguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980070/ https://www.ncbi.nlm.nih.gov/pubmed/35379798 http://dx.doi.org/10.1038/s41419-022-04773-1

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