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Nuplazid suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting PAK4

BACKGROUND: Due to the high recurrence and low 5-year survival rates of esophageal squamous cell carcinoma (ESCC) after treatment, the discovery of novel drugs for recurrence chemoprevention is of particular importance. METHODS: We screened the FDA-approved drug library and found that Nuplazid, an a...

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Detalles Bibliográficos
Autores principales:	Wei, Yaxing, Wu, Wenjie, Jiang, Yanan, Zhou, Hao, Yu, Yin, Zhao, Lili, Wu, Xiangyu, Lu, Xuebo, Yuan, Qiang, Wang, Zitong, Dong, Zigang, He, Luyun, Zhao, Jimin, Liu, Kangdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980085/ https://www.ncbi.nlm.nih.gov/pubmed/34912075 http://dx.doi.org/10.1038/s41416-021-01651-z

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