A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic of novel coronavirus disease (COVID-19). The neutralizing monoclonal antibodies (mAbs) targeting the receptor-binding domain (RBD) of SARS-CoV-2 are among the most promising strategies to prevent and treat...

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Detalles Bibliográficos
Autores principales: Wang, Xiaofei, Hu, Ao, Chen, Xiangyu, Zhang, Yixin, Yu, Fei, Yue, Shuai, Li, Arong, Zhang, Junsong, Pan, Zhiwei, Yang, Yang, Lin, Yao, Gao, Leiqiong, Zhou, Jing, Zhao, Jing, Li, Fang, Shi, Yaling, Huang, Feng, Yang, Xiaofan, Peng, Yi, Tu, Luoyang, Zhang, Huan, Zheng, Huanying, He, Jun, Zhang, Hui, Xu, Lifan, Huang, Qizhao, Zhu, Yongqun, Deng, Kai, Ye, Lilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980211/
https://www.ncbi.nlm.nih.gov/pubmed/35383141
http://dx.doi.org/10.1038/s41392-022-00954-8

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