Cargando…

Amplatzer Patent Foramen Ovale Occluder Device-Related Complications

Patent foramen ovale (PFO) is a standard variant that is present in 25% of the whole adult population. In a certain population, PFO can lead to cerebrovascular accidents. Mechanism of cerebrovascular accidents can be by paradoxical embolization from the right circulation or in situ thrombosis. Diagn...

Descripción completa

Detalles Bibliográficos
Autores principales: Iskander, Beshoy, Anwer, Fatima, Oliveri, Federico, Fotios, Kakargias, Panday, Priyanka, Arcia Franchini, Ana P, Hamid, Pousette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980243/
https://www.ncbi.nlm.nih.gov/pubmed/35402119
http://dx.doi.org/10.7759/cureus.23756
_version_ 1784681346787966976
author Iskander, Beshoy
Anwer, Fatima
Oliveri, Federico
Fotios, Kakargias
Panday, Priyanka
Arcia Franchini, Ana P
Hamid, Pousette
author_facet Iskander, Beshoy
Anwer, Fatima
Oliveri, Federico
Fotios, Kakargias
Panday, Priyanka
Arcia Franchini, Ana P
Hamid, Pousette
author_sort Iskander, Beshoy
collection PubMed
description Patent foramen ovale (PFO) is a standard variant that is present in 25% of the whole adult population. In a certain population, PFO can lead to cerebrovascular accidents. Mechanism of cerebrovascular accidents can be by paradoxical embolization from the right circulation or in situ thrombosis. Diagnosis of a PFO-responsible cerebrovascular accident is based on a thorough work-up to exclude other possible etiologies and detect PFO on trans-thoracic or trans-esophageal echocardiography with bubble study and/or Doppler. Over the last few years, multiple studies have supported that percutaneous PFO closure is superior to medical therapy in the secondary prevention of cerebrovascular accidents. However, numerous adverse events have been linked to PFO closure devices in general compared to medical therapy as new-onset atrial fibrillation, residual shunt, device-related thrombus, bleeding, deep vein thrombosis, pulmonary embolism, and inter-atrial septal erosions. Amplatzer device is one of the PFO occluder devices approved by the FDA. Device-related adverse events have been addressed by comparing the Amplatzer device with other PFO occluder devices. Based on the new data, we expect to see more complications related to PFO closure in the coming few years. We reviewed different studies that looked at the PFO closure-related complications and the trials comparing adverse events in the Amplatzer PFO occluder device compared to other devices. Amplatzer PFO occluder device is either superior or non-statistically different from other PFO occluder devices related to new-onset atrial fibrillation and residual shunt. More studies are needed to address the other less common adverse events. Since many of the device-related complications appear many years after device placement, a long-term follow-up is recommended.
format Online
Article
Text
id pubmed-8980243
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-89802432022-04-07 Amplatzer Patent Foramen Ovale Occluder Device-Related Complications Iskander, Beshoy Anwer, Fatima Oliveri, Federico Fotios, Kakargias Panday, Priyanka Arcia Franchini, Ana P Hamid, Pousette Cureus Cardiac/Thoracic/Vascular Surgery Patent foramen ovale (PFO) is a standard variant that is present in 25% of the whole adult population. In a certain population, PFO can lead to cerebrovascular accidents. Mechanism of cerebrovascular accidents can be by paradoxical embolization from the right circulation or in situ thrombosis. Diagnosis of a PFO-responsible cerebrovascular accident is based on a thorough work-up to exclude other possible etiologies and detect PFO on trans-thoracic or trans-esophageal echocardiography with bubble study and/or Doppler. Over the last few years, multiple studies have supported that percutaneous PFO closure is superior to medical therapy in the secondary prevention of cerebrovascular accidents. However, numerous adverse events have been linked to PFO closure devices in general compared to medical therapy as new-onset atrial fibrillation, residual shunt, device-related thrombus, bleeding, deep vein thrombosis, pulmonary embolism, and inter-atrial septal erosions. Amplatzer device is one of the PFO occluder devices approved by the FDA. Device-related adverse events have been addressed by comparing the Amplatzer device with other PFO occluder devices. Based on the new data, we expect to see more complications related to PFO closure in the coming few years. We reviewed different studies that looked at the PFO closure-related complications and the trials comparing adverse events in the Amplatzer PFO occluder device compared to other devices. Amplatzer PFO occluder device is either superior or non-statistically different from other PFO occluder devices related to new-onset atrial fibrillation and residual shunt. More studies are needed to address the other less common adverse events. Since many of the device-related complications appear many years after device placement, a long-term follow-up is recommended. Cureus 2022-04-02 /pmc/articles/PMC8980243/ /pubmed/35402119 http://dx.doi.org/10.7759/cureus.23756 Text en Copyright © 2022, Iskander et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiac/Thoracic/Vascular Surgery
Iskander, Beshoy
Anwer, Fatima
Oliveri, Federico
Fotios, Kakargias
Panday, Priyanka
Arcia Franchini, Ana P
Hamid, Pousette
Amplatzer Patent Foramen Ovale Occluder Device-Related Complications
title Amplatzer Patent Foramen Ovale Occluder Device-Related Complications
title_full Amplatzer Patent Foramen Ovale Occluder Device-Related Complications
title_fullStr Amplatzer Patent Foramen Ovale Occluder Device-Related Complications
title_full_unstemmed Amplatzer Patent Foramen Ovale Occluder Device-Related Complications
title_short Amplatzer Patent Foramen Ovale Occluder Device-Related Complications
title_sort amplatzer patent foramen ovale occluder device-related complications
topic Cardiac/Thoracic/Vascular Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980243/
https://www.ncbi.nlm.nih.gov/pubmed/35402119
http://dx.doi.org/10.7759/cureus.23756
work_keys_str_mv AT iskanderbeshoy amplatzerpatentforamenovaleoccluderdevicerelatedcomplications
AT anwerfatima amplatzerpatentforamenovaleoccluderdevicerelatedcomplications
AT oliverifederico amplatzerpatentforamenovaleoccluderdevicerelatedcomplications
AT fotioskakargias amplatzerpatentforamenovaleoccluderdevicerelatedcomplications
AT pandaypriyanka amplatzerpatentforamenovaleoccluderdevicerelatedcomplications
AT arciafranchinianap amplatzerpatentforamenovaleoccluderdevicerelatedcomplications
AT hamidpousette amplatzerpatentforamenovaleoccluderdevicerelatedcomplications