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Amplatzer Patent Foramen Ovale Occluder Device-Related Complications
Patent foramen ovale (PFO) is a standard variant that is present in 25% of the whole adult population. In a certain population, PFO can lead to cerebrovascular accidents. Mechanism of cerebrovascular accidents can be by paradoxical embolization from the right circulation or in situ thrombosis. Diagn...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980243/ https://www.ncbi.nlm.nih.gov/pubmed/35402119 http://dx.doi.org/10.7759/cureus.23756 |
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author | Iskander, Beshoy Anwer, Fatima Oliveri, Federico Fotios, Kakargias Panday, Priyanka Arcia Franchini, Ana P Hamid, Pousette |
author_facet | Iskander, Beshoy Anwer, Fatima Oliveri, Federico Fotios, Kakargias Panday, Priyanka Arcia Franchini, Ana P Hamid, Pousette |
author_sort | Iskander, Beshoy |
collection | PubMed |
description | Patent foramen ovale (PFO) is a standard variant that is present in 25% of the whole adult population. In a certain population, PFO can lead to cerebrovascular accidents. Mechanism of cerebrovascular accidents can be by paradoxical embolization from the right circulation or in situ thrombosis. Diagnosis of a PFO-responsible cerebrovascular accident is based on a thorough work-up to exclude other possible etiologies and detect PFO on trans-thoracic or trans-esophageal echocardiography with bubble study and/or Doppler. Over the last few years, multiple studies have supported that percutaneous PFO closure is superior to medical therapy in the secondary prevention of cerebrovascular accidents. However, numerous adverse events have been linked to PFO closure devices in general compared to medical therapy as new-onset atrial fibrillation, residual shunt, device-related thrombus, bleeding, deep vein thrombosis, pulmonary embolism, and inter-atrial septal erosions. Amplatzer device is one of the PFO occluder devices approved by the FDA. Device-related adverse events have been addressed by comparing the Amplatzer device with other PFO occluder devices. Based on the new data, we expect to see more complications related to PFO closure in the coming few years. We reviewed different studies that looked at the PFO closure-related complications and the trials comparing adverse events in the Amplatzer PFO occluder device compared to other devices. Amplatzer PFO occluder device is either superior or non-statistically different from other PFO occluder devices related to new-onset atrial fibrillation and residual shunt. More studies are needed to address the other less common adverse events. Since many of the device-related complications appear many years after device placement, a long-term follow-up is recommended. |
format | Online Article Text |
id | pubmed-8980243 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-89802432022-04-07 Amplatzer Patent Foramen Ovale Occluder Device-Related Complications Iskander, Beshoy Anwer, Fatima Oliveri, Federico Fotios, Kakargias Panday, Priyanka Arcia Franchini, Ana P Hamid, Pousette Cureus Cardiac/Thoracic/Vascular Surgery Patent foramen ovale (PFO) is a standard variant that is present in 25% of the whole adult population. In a certain population, PFO can lead to cerebrovascular accidents. Mechanism of cerebrovascular accidents can be by paradoxical embolization from the right circulation or in situ thrombosis. Diagnosis of a PFO-responsible cerebrovascular accident is based on a thorough work-up to exclude other possible etiologies and detect PFO on trans-thoracic or trans-esophageal echocardiography with bubble study and/or Doppler. Over the last few years, multiple studies have supported that percutaneous PFO closure is superior to medical therapy in the secondary prevention of cerebrovascular accidents. However, numerous adverse events have been linked to PFO closure devices in general compared to medical therapy as new-onset atrial fibrillation, residual shunt, device-related thrombus, bleeding, deep vein thrombosis, pulmonary embolism, and inter-atrial septal erosions. Amplatzer device is one of the PFO occluder devices approved by the FDA. Device-related adverse events have been addressed by comparing the Amplatzer device with other PFO occluder devices. Based on the new data, we expect to see more complications related to PFO closure in the coming few years. We reviewed different studies that looked at the PFO closure-related complications and the trials comparing adverse events in the Amplatzer PFO occluder device compared to other devices. Amplatzer PFO occluder device is either superior or non-statistically different from other PFO occluder devices related to new-onset atrial fibrillation and residual shunt. More studies are needed to address the other less common adverse events. Since many of the device-related complications appear many years after device placement, a long-term follow-up is recommended. Cureus 2022-04-02 /pmc/articles/PMC8980243/ /pubmed/35402119 http://dx.doi.org/10.7759/cureus.23756 Text en Copyright © 2022, Iskander et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiac/Thoracic/Vascular Surgery Iskander, Beshoy Anwer, Fatima Oliveri, Federico Fotios, Kakargias Panday, Priyanka Arcia Franchini, Ana P Hamid, Pousette Amplatzer Patent Foramen Ovale Occluder Device-Related Complications |
title | Amplatzer Patent Foramen Ovale Occluder Device-Related Complications |
title_full | Amplatzer Patent Foramen Ovale Occluder Device-Related Complications |
title_fullStr | Amplatzer Patent Foramen Ovale Occluder Device-Related Complications |
title_full_unstemmed | Amplatzer Patent Foramen Ovale Occluder Device-Related Complications |
title_short | Amplatzer Patent Foramen Ovale Occluder Device-Related Complications |
title_sort | amplatzer patent foramen ovale occluder device-related complications |
topic | Cardiac/Thoracic/Vascular Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980243/ https://www.ncbi.nlm.nih.gov/pubmed/35402119 http://dx.doi.org/10.7759/cureus.23756 |
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