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Osthole-Mediated Inhibition of Neurotoxicity Induced by Ropivacaine via Amplification of the Cyclic Adenosine Monophosphate Signaling Pathway

BACKGROUND: Ropivacaine is widely used for clinical anesthesia and postoperative analgesia. However, the neurotoxicity induced by ropivacaine in a concentration- and duration-dependent manner, and it is difficult to prevent neurotoxicity. Osthole inhibits phosphodiesterase-4 activity by binding to i...

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Detalles Bibliográficos
Autores principales:	Wang, WeiBing, Zhou, Hui, Sun, LaiBao, Li, MeiNa, Gao, FengJiao, Sun, AiJiao, Zou, XueNong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	External
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980408/ https://www.ncbi.nlm.nih.gov/pubmed/35392264 http://dx.doi.org/10.1177/15593258221088092

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