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A bioluminescence reporter mouse model for visualizing and quantifying CD8+ T cells in vivo
Cytotoxic CD8+ T cells are the primary effector cells mediating anti-tumor responses. In vivo monitoring of CD8+ T cells has broad implications for the development of novel cancer therapies. Here we describe the development of a genetically engineered mouse model (GEMM) in which CD8+ T cells are lab...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980487/ https://www.ncbi.nlm.nih.gov/pubmed/35381456 http://dx.doi.org/10.1016/j.neo.2022.100781 |