A bioluminescence reporter mouse model for visualizing and quantifying CD8+ T cells in vivo

Cytotoxic CD8+ T cells are the primary effector cells mediating anti-tumor responses. In vivo monitoring of CD8+ T cells has broad implications for the development of novel cancer therapies. Here we describe the development of a genetically engineered mouse model (GEMM) in which CD8+ T cells are lab...

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Detalles Bibliográficos
Autores principales: Bettano, Kimberly, Zielstorff, Mark, Sevilla, Raquel, Yang, Ruojing, Zhou, Heather, Rosahl, Thomas, Zhang-Hoover, Jie, Moy, Lily Y., Zhang, Weisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980487/
https://www.ncbi.nlm.nih.gov/pubmed/35381456
http://dx.doi.org/10.1016/j.neo.2022.100781

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