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Defect self-assembly of metal-organic framework triggers ferroptosis to overcome resistance

The emergence of multidrug treatment resistance presents a hurdle for the successful chemotherapy of tumours. Ferroptosis, resulting from the iron-dependent accumulation of lipid peroxides, has the potential to reverse multidrug resistance. However, simultaneous delivery of the iron sources, ferropt...

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Detalles Bibliográficos
Autores principales: Peng, Haibao, Zhang, Xingcai, Yang, Peng, Zhao, Jiaxu, Zhang, Wei, Feng, Nianping, Yang, Wuli, Tang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980498/
https://www.ncbi.nlm.nih.gov/pubmed/35415315
http://dx.doi.org/10.1016/j.bioactmat.2021.12.018