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Comparison Between the Physical Performance Test and the Clinical Frailty Score in Adult Patients With Chronic Kidney Disease Treated by Haemodialysis

Elderly patients with chronic kidney disease treated by haemodialysis are at increased risk of malnutrition and cachexia, becoming frail, with associated greater mortality. The physical performance test (PPT), using nine tasks to assess multiple domains of physical function is robust and reproducibl...

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Autor principal: Davenport, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980538/
https://www.ncbi.nlm.nih.gov/pubmed/35392161
http://dx.doi.org/10.1177/23337214221085875
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author Davenport, Andrew
author_facet Davenport, Andrew
author_sort Davenport, Andrew
collection PubMed
description Elderly patients with chronic kidney disease treated by haemodialysis are at increased risk of malnutrition and cachexia, becoming frail, with associated greater mortality. The physical performance test (PPT), using nine tasks to assess multiple domains of physical function is robust and reproducible, but time consuming, whereas the clinical frailty score (CFS) is more rapid. We compared the results from independent blinded observers in 22 haemodialysis patients, 16 (72.7%) male, mean age 65 ± 12.5 years. The PPT and CFS scores were highly correlated (r = −0.88, p < .001), with a high level of agreement (kappa score 0.91) for classifying patients as frail. Both scores were strongly associated with serum creatinine (PPT r=0.76, CFS r=−0.86, p < .001), hand grip strength (PPT r = 0.68, p = .001 CFS r = 0.64, p = .002), lean body mass index (PPT r = 0.50, p = .02, CFS r = −0.46, p = .038). We found that the CFS performed favourably compared to the PPT for haemodialysis patients in identifying and screening patients for frailty.
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spelling pubmed-89805382022-04-06 Comparison Between the Physical Performance Test and the Clinical Frailty Score in Adult Patients With Chronic Kidney Disease Treated by Haemodialysis Davenport, Andrew Gerontol Geriatr Med Brief Report Elderly patients with chronic kidney disease treated by haemodialysis are at increased risk of malnutrition and cachexia, becoming frail, with associated greater mortality. The physical performance test (PPT), using nine tasks to assess multiple domains of physical function is robust and reproducible, but time consuming, whereas the clinical frailty score (CFS) is more rapid. We compared the results from independent blinded observers in 22 haemodialysis patients, 16 (72.7%) male, mean age 65 ± 12.5 years. The PPT and CFS scores were highly correlated (r = −0.88, p < .001), with a high level of agreement (kappa score 0.91) for classifying patients as frail. Both scores were strongly associated with serum creatinine (PPT r=0.76, CFS r=−0.86, p < .001), hand grip strength (PPT r = 0.68, p = .001 CFS r = 0.64, p = .002), lean body mass index (PPT r = 0.50, p = .02, CFS r = −0.46, p = .038). We found that the CFS performed favourably compared to the PPT for haemodialysis patients in identifying and screening patients for frailty. SAGE Publications 2022-03-28 /pmc/articles/PMC8980538/ /pubmed/35392161 http://dx.doi.org/10.1177/23337214221085875 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Brief Report
Davenport, Andrew
Comparison Between the Physical Performance Test and the Clinical Frailty Score in Adult Patients With Chronic Kidney Disease Treated by Haemodialysis
title Comparison Between the Physical Performance Test and the Clinical Frailty Score in Adult Patients With Chronic Kidney Disease Treated by Haemodialysis
title_full Comparison Between the Physical Performance Test and the Clinical Frailty Score in Adult Patients With Chronic Kidney Disease Treated by Haemodialysis
title_fullStr Comparison Between the Physical Performance Test and the Clinical Frailty Score in Adult Patients With Chronic Kidney Disease Treated by Haemodialysis
title_full_unstemmed Comparison Between the Physical Performance Test and the Clinical Frailty Score in Adult Patients With Chronic Kidney Disease Treated by Haemodialysis
title_short Comparison Between the Physical Performance Test and the Clinical Frailty Score in Adult Patients With Chronic Kidney Disease Treated by Haemodialysis
title_sort comparison between the physical performance test and the clinical frailty score in adult patients with chronic kidney disease treated by haemodialysis
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980538/
https://www.ncbi.nlm.nih.gov/pubmed/35392161
http://dx.doi.org/10.1177/23337214221085875
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