c-Abl kinase-mediated phosphorylation of γ-tubulin promotes γ-tubulin ring complexes assembly and microtubule nucleation

Cytoskeletal microtubules (MTs) are nucleated from γ-tubulin ring complexes (γTuRCs) located at MT organizing centers (MTOCs), such as the centrosome. However, the exact regulatory mechanism of γTuRC assembly is not fully understood. Here, we showed that the nonreceptor tyrosine kinase c-Abl was ass...

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Detalles Bibliográficos
Autores principales: Wang, Guang-Fei, Dong, Qincai, Bai, Yu, Gu, Jing, Tao, Qingping, Yue, Junjie, Zhou, Rui, Niu, Xiayang, Zhu, Lin, Song, Caiwei, Zheng, Tong, Wang, Di, Jin, Yanwen, Liu, Hainan, Cao, Cheng, Liu, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980629/
https://www.ncbi.nlm.nih.gov/pubmed/35231444
http://dx.doi.org/10.1016/j.jbc.2022.101778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980629/
https://www.ncbi.nlm.nih.gov/pubmed/35231444
http://dx.doi.org/10.1016/j.jbc.2022.101778

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