Single-Cell Transcriptomics of Cultured Amniotic Fluid Cells Reveals Complex Gene Expression Alterations in Human Fetuses With Trisomy 18

Trisomy 18, commonly known as Edwards syndrome, is the second most common autosomal trisomy among live born neonates. Multiple tissues including cardiac, abdominal, and nervous systems are affected by an extra chromosome 18. To delineate the complexity of anomalies of trisomy 18, we analyzed culture...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Chen, Zixi, He, Fei, Lee, Trevor, Cai, Wenjie, Chen, Wanhua, Miao, Nan, Zeng, Zhiwei, Hussain, Ghulam, Yang, Qingwei, Guo, Qiwei, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980718/
https://www.ncbi.nlm.nih.gov/pubmed/35392164
http://dx.doi.org/10.3389/fcell.2022.825345

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