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Downregulation of neurodevelopmental gene expression in iPSC-derived cerebral organoids upon infection by human cytomegalovirus

Human cytomegalovirus (HCMV) is a betaherpesvirus that can cause severe birth defects including vision and hearing loss, microcephaly, and seizures. Currently, no approved treatment options exist for in utero infections. Here, we aimed to determine the impact of HCMV infection on the transcriptome o...

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Detalles Bibliográficos
Autores principales:	O’Brien, Benjamin S., Mokry, Rebekah L., Schumacher, Megan L., Pulakanti, Kirthi, Rao, Sridhar, Terhune, Scott S., Ebert, Allison D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980761/ https://www.ncbi.nlm.nih.gov/pubmed/35391828 http://dx.doi.org/10.1016/j.isci.2022.104098

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