Cargando…

Methyltransferase METTL8 is required for 3-methylcytosine modification in human mitochondrial tRNAs

A subset of eukaryotic tRNAs is methylated in the anticodon loop, forming 3-methylcytosine (m(3)C) modifications. In mammals, the number of tRNAs containing m(3)C modifications has been expanded to include mitochondrial (mt) tRNA-Ser-UGA and mt-tRNA-Thr-UGU. However, whereas the enzymes catalyzing m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lentini, Jenna M., Bargabos, Rachel, Chen, Chen, Fu, Dragony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980813/ https://www.ncbi.nlm.nih.gov/pubmed/35247384 http://dx.doi.org/10.1016/j.jbc.2022.101788

Ejemplares similares

DALRD3 encodes a protein mutated in epileptic encephalopathy that targets arginine tRNAs for 3-methylcytosine modification
por: Lentini, Jenna M., et al.
Publicado: (2020)

Monitoring the 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) modification in eukaryotic tRNAs via the γ-toxin endonuclease
por: Lentini, Jenna M., et al.
Publicado: (2018)

NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs
por: Van Haute, Lindsey, et al.
Publicado: (2019)

The RNA methyltransferase METTL8 installs m(3)C(32) in mitochondrial tRNAs(Thr/Ser(UCN)) to optimise tRNA structure and mitochondrial translation
por: Kleiber, Nicole, et al.
Publicado: (2022)

Maturation of selected human mitochondrial tRNAs requires deadenylation
por: Pearce, Sarah F, et al.
Publicado: (2017)

An extended dsRBD is required for post-transcriptional modification in human tRNAs
por: Bou-Nader, Charles, et al.
Publicado: (2015)

Biosynthesis and Degradation of Sulfur Modifications in tRNAs
por: Shigi, Naoki
Publicado: (2021)

A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs
por: Suzuki, Takeo, et al.
Publicado: (2014)

Undetected antisense tRNAs in mitochondrial genomes?
por: Seligmann, Hervé
Publicado: (2010)

Armless mitochondrial tRNAs in Enoplea (Nematoda)
por: Jühling, Frank, et al.
Publicado: (2012)

Tissue-specific expression atlas of murine mitochondrial tRNAs
por: He, Qiufen, et al.
Publicado: (2021)

Mechanism of expanding the decoding capacity of tRNAs by modification of uridines
por: Weixlbaumer, Albert, et al.
Publicado: (2007)

m(1)A Post-Transcriptional Modification in tRNAs
por: Oerum, Stephanie, et al.
Publicado: (2017)

To be or not to be modified: Miscellaneous aspects influencing nucleotide modifications in tRNAs
por: Barraud, Pierre, et al.
Publicado: (2019)

Complete chemical structures of human mitochondrial tRNAs
por: Suzuki, Takeo, et al.
Publicado: (2020)

5-methylcytosine RNA methyltransferases and their potential roles in cancer
por: Li, Mingyang, et al.
Publicado: (2022)

Retrograde tRNAs
por: Tuma, Rabiya S.
Publicado: (2005)

Nuclear-encoded factors involved in post-transcriptional processing and modification of mitochondrial tRNAs in human disease
por: Powell, Christopher A., et al.
Publicado: (2015)

Modification of orthogonal tRNAs: unexpected consequences for sense codon reassignment
por: Biddle, Wil, et al.
Publicado: (2016)

Queuosine modification protects cognate tRNAs against ribonuclease cleavage
por: Wang, Xiaoyun, et al.
Publicado: (2018)

Recent Advances in Our Understanding of the Biosynthesis of Sulfur Modifications in tRNAs
por: Shigi, Naoki
Publicado: (2018)

Bioinformatics analysis suggests base modifications of tRNAs and miRNAs in Arabidopsis thaliana
por: Iida, Kei, et al.
Publicado: (2009)

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
por: Davydova, Erna, et al.
Publicado: (2021)

Human METTL12 is a mitochondrial methyltransferase that modifies citrate synthase
por: Rhein, Virginie F., et al.
Publicado: (2017)

tRNAs as Antibiotic Targets
por: Chopra, Shaileja, et al.
Publicado: (2014)

tRNAs taking charge
por: Cruz, Jonathan W., et al.
Publicado: (2015)

Hijacking tRNAs From Translation: Regulatory Functions of tRNAs in Mammalian Cell Physiology
por: Avcilar-Kucukgoze, Irem, et al.
Publicado: (2020)

Inosine modifications in human tRNAs are incorporated at the precursor tRNA level
por: Torres, Adrian Gabriel, et al.
Publicado: (2015)

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury
por: Wu, Yong, et al.
Publicado: (2016)

Polyadenylation and degradation of structurally abnormal mitochondrial tRNAs in human cells
por: Toompuu, Marina, et al.
Publicado: (2018)

Back to Water: Signature of Adaptive Evolution in Cetacean Mitochondrial tRNAs
por: Montelli, Stefano, et al.
Publicado: (2016)

Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs
por: Shinoda, Saori, et al.
Publicado: (2019)

Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing
por: Hoser, Simon M., et al.
Publicado: (2020)

Modification at position 9 with 1-methyladenosine is crucial for structure and function of nematode mitochondrial tRNAs lacking the entire T-arm
por: Sakurai, Masayuki, et al.
Publicado: (2005)

Phylogeny and evolution of chloroplast tRNAs in Adoxaceae
por: Zhong, Qiu‐Yi, et al.
Publicado: (2021)

Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120
por: Bourgeois, Gabrielle, et al.
Publicado: (2015)

Expanded tRNA methyltransferase family member TRMT9B regulates synaptic growth and function
por: Hogan, Caley A, et al.
Publicado: (2023)

Bacterial noncoding Y RNAs are widespread and mimic tRNAs
por: Chen, Xinguo, et al.
Publicado: (2014)

A polyhedron made of tRNAs
por: Severcan, Isil, et al.
Publicado: (2010)

Genomic organization of eukaryotic tRNAs
por: Bermudez-Santana, Clara, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_4731ih51m37o0c2eo4i6nkokj6