Diffuse alveolar haemorrhage as a rare complication of antiphospholipid syndrome

Diffuse alveolar haemorrhage (DAH) is a rare complication of antiphospholipid syndrome. With a mortality rate of 46%, early diagnosis and management remain an ongoing challenge. Case reports are limited, and management guidelines are not yet definitive. In this case report, we present a 43‐year‐old...

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Autores principales: Seth, Ishith, Bhagavata Srinivasan, Shyam Prakaash, Bulloch, Gabriella, Yi, Dong Seok, Frankel, Anthony, Hsu, Kelvin, Passam, Freda, Garsia, Roger, Corte, Tamera J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980908/
https://www.ncbi.nlm.nih.gov/pubmed/35414937
http://dx.doi.org/10.1002/rcr2.948
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author Seth, Ishith
Bhagavata Srinivasan, Shyam Prakaash
Bulloch, Gabriella
Yi, Dong Seok
Frankel, Anthony
Hsu, Kelvin
Passam, Freda
Garsia, Roger
Corte, Tamera J.
author_facet Seth, Ishith
Bhagavata Srinivasan, Shyam Prakaash
Bulloch, Gabriella
Yi, Dong Seok
Frankel, Anthony
Hsu, Kelvin
Passam, Freda
Garsia, Roger
Corte, Tamera J.
author_sort Seth, Ishith
collection PubMed
description Diffuse alveolar haemorrhage (DAH) is a rare complication of antiphospholipid syndrome. With a mortality rate of 46%, early diagnosis and management remain an ongoing challenge. Case reports are limited, and management guidelines are not yet definitive. In this case report, we present a 43‐year‐old male with DAH who required high‐dose oral steroids, intravenous methylprednisolone cyclophosphamide and rituximab over 18 months to control life‐threatening episodes of pulmonary bleeding.
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spelling pubmed-89809082022-04-11 Diffuse alveolar haemorrhage as a rare complication of antiphospholipid syndrome Seth, Ishith Bhagavata Srinivasan, Shyam Prakaash Bulloch, Gabriella Yi, Dong Seok Frankel, Anthony Hsu, Kelvin Passam, Freda Garsia, Roger Corte, Tamera J. Respirol Case Rep Case Reports Diffuse alveolar haemorrhage (DAH) is a rare complication of antiphospholipid syndrome. With a mortality rate of 46%, early diagnosis and management remain an ongoing challenge. Case reports are limited, and management guidelines are not yet definitive. In this case report, we present a 43‐year‐old male with DAH who required high‐dose oral steroids, intravenous methylprednisolone cyclophosphamide and rituximab over 18 months to control life‐threatening episodes of pulmonary bleeding. John Wiley & Sons, Ltd 2022-04-05 /pmc/articles/PMC8980908/ /pubmed/35414937 http://dx.doi.org/10.1002/rcr2.948 Text en © 2022 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Seth, Ishith
Bhagavata Srinivasan, Shyam Prakaash
Bulloch, Gabriella
Yi, Dong Seok
Frankel, Anthony
Hsu, Kelvin
Passam, Freda
Garsia, Roger
Corte, Tamera J.
Diffuse alveolar haemorrhage as a rare complication of antiphospholipid syndrome
title Diffuse alveolar haemorrhage as a rare complication of antiphospholipid syndrome
title_full Diffuse alveolar haemorrhage as a rare complication of antiphospholipid syndrome
title_fullStr Diffuse alveolar haemorrhage as a rare complication of antiphospholipid syndrome
title_full_unstemmed Diffuse alveolar haemorrhage as a rare complication of antiphospholipid syndrome
title_short Diffuse alveolar haemorrhage as a rare complication of antiphospholipid syndrome
title_sort diffuse alveolar haemorrhage as a rare complication of antiphospholipid syndrome
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980908/
https://www.ncbi.nlm.nih.gov/pubmed/35414937
http://dx.doi.org/10.1002/rcr2.948
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