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8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Exacerbates Doxorubicin-Induced Cardiac Dysfunction

Doxorubicin is an anthracycline widely used for the treatment of various cancers; however, the drug has a common deleterious side effect, namely a dose-dependent cardiotoxicity. Doxorubicin treatment increases the generation of reactive oxygen species, which leads to oxidative stress in the cardiac...

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Detalles Bibliográficos
Autores principales:	Anene-Nzelu, Chukwuemeka George, Li, Peter Yiqing, Luu, Tuan Danh Anh, Ng, Shi Ling, Tiang, Zenia, Pan, Bangfen, Tan, Wilson Lek Wen, Ackers-Johnson, Matthew, Chen, Ching Kit, Lim, Yee Phong, Qin, Rina Wang Miao, Chua, Wee Woon, Yi, Lim Xin, Foo, Roger Sik-Yin, Nakabeppu, Yusaku
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981022/ https://www.ncbi.nlm.nih.gov/pubmed/35391931 http://dx.doi.org/10.1155/2022/9180267

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