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Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments

Epstein-Barr virus (EBV) persistently infects people worldwide. Delivery of ~170-kb EBV genomes to nuclei and use of nuclear membrane-less replication compartments (RCs) for their lytic cycle amplification necessitate evasion of intrinsic antiviral responses. Proteomics analysis indicates that, upon...

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Detalles Bibliográficos
Autores principales: Tung Yiu, Stephanie Pei, Guo, Rui, Zerbe, Cassie, Weekes, Michael P., Gewurz, Benjamin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981113/
https://www.ncbi.nlm.nih.gov/pubmed/35263599
http://dx.doi.org/10.1016/j.celrep.2022.110411

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