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Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments
Epstein-Barr virus (EBV) persistently infects people worldwide. Delivery of ~170-kb EBV genomes to nuclei and use of nuclear membrane-less replication compartments (RCs) for their lytic cycle amplification necessitate evasion of intrinsic antiviral responses. Proteomics analysis indicates that, upon...
Autores principales: | Tung Yiu, Stephanie Pei, Guo, Rui, Zerbe, Cassie, Weekes, Michael P., Gewurz, Benjamin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981113/ https://www.ncbi.nlm.nih.gov/pubmed/35263599 http://dx.doi.org/10.1016/j.celrep.2022.110411 |
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