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Toward Zero Variance in Proteomics Sample Preparation: Positive-Pressure FASP in 96-Well Format (PF96) Enables Highly Reproducible, Time- and Cost-Efficient Analysis of Sample Cohorts

[Image: see text] As novel liquid chromatography–mass spectrometry (LC-MS) technologies for proteomics offer a substantial increase in LC-MS runs per day, robust and reproducible sample preparation emerges as a new bottleneck for throughput. We introduce a novel strategy for positive-pressure 96-wel...

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Detalles Bibliográficos
Autores principales: Loroch, Stefan, Kopczynski, Dominik, Schneider, Adriana C., Schumbrutzki, Cornelia, Feldmann, Ingo, Panagiotidis, Eleftherios, Reinders, Yvonne, Sakson, Roman, Solari, Fiorella A., Vening, Alicia, Swieringa, Frauke, Heemskerk, Johan W. M., Grandoch, Maria, Dandekar, Thomas, Sickmann, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981309/
https://www.ncbi.nlm.nih.gov/pubmed/35316605
http://dx.doi.org/10.1021/acs.jproteome.1c00706