A Chemo- and Regioselective Tandem [3 + 2]Heteroannulation Strategy for Carbazole Synthesis: Combining Two Mechanistically Distinct Bond-Forming Processes

[Image: see text] A modular approach to prepare tri- and tetracyclic carbazoles by a sequential [3 + 2]heteroannulation is described. First, optimization of Pd-catalyzed Buchwald–Hartwig amination followed by C/N-arylation in a one-pot process is established. Second, mechanistic analyses identified...

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Detalles Bibliográficos
Autores principales: Campbell, Emma, Taladriz-Sender, Andrea, Paisley, Olivia I., Kennedy, Alan R., Bush, Jacob T., Burley, Glenn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981337/
https://www.ncbi.nlm.nih.gov/pubmed/35302774
http://dx.doi.org/10.1021/acs.joc.1c02943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981337/
https://www.ncbi.nlm.nih.gov/pubmed/35302774
http://dx.doi.org/10.1021/acs.joc.1c02943

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