Highly efficient synthesis of 3,4-diarylbutadiene sulfones using Heck–Matsuda reaction

For the first time we describe a general method for the synthesis of previously not synthesized unsymmetrical 3,4-diarylbutadiene sulfones which can be stable convenient precursors for 2,3-diaryl-1,3-butadienes. Our method for arylation of butadiene sulfones via Heck–Matsuda reaction allows to obtai...

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Detalles Bibliográficos
Autores principales: Shurupova, Olga V., Rzhevskiy, Sergey A., Minaeva, Lidiya I., Topchiy, Maxim A., Asachenko, Andrey F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981374/
https://www.ncbi.nlm.nih.gov/pubmed/35425582
http://dx.doi.org/10.1039/d2ra00078d
Descripción
Sumario:For the first time we describe a general method for the synthesis of previously not synthesized unsymmetrical 3,4-diarylbutadiene sulfones which can be stable convenient precursors for 2,3-diaryl-1,3-butadienes. Our method for arylation of butadiene sulfones via Heck–Matsuda reaction allows to obtain unsymmetrical 3,4-diarylbutadiene sulfones with a variety of alkyl, alkoxy, nitro, ethoxycarbonyl, perfluoroalkyl and halogen substituents (30 examples) in very good yields using readily available reagents and catalysts.

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