Simulations reveal that antimicrobial BP100 induces local membrane thinning, slows lipid dynamics and favors water penetration

BP100, a short antimicrobial peptide, produces membrane perturbations that depend on lipid structure and charge, salts presence, and peptide/lipid molar ratios. As membrane perturbation mechanisms are not fully understood, the atomic scale nature of peptide/membrane interactions requires a close-up...

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Detalles Bibliográficos
Autores principales: Franco, Leandro R., Park, Peter, Chaimovich, Hernan, Coutinho, Kaline, Cuccovia, Iolanda M., Lima, Filipe S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981376/
https://www.ncbi.nlm.nih.gov/pubmed/35425494
http://dx.doi.org/10.1039/d1ra06267k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981376/
https://www.ncbi.nlm.nih.gov/pubmed/35425494
http://dx.doi.org/10.1039/d1ra06267k

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