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Simulations reveal that antimicrobial BP100 induces local membrane thinning, slows lipid dynamics and favors water penetration
BP100, a short antimicrobial peptide, produces membrane perturbations that depend on lipid structure and charge, salts presence, and peptide/lipid molar ratios. As membrane perturbation mechanisms are not fully understood, the atomic scale nature of peptide/membrane interactions requires a close-up...
Autores principales: | Franco, Leandro R., Park, Peter, Chaimovich, Hernan, Coutinho, Kaline, Cuccovia, Iolanda M., Lima, Filipe S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981376/ https://www.ncbi.nlm.nih.gov/pubmed/35425494 http://dx.doi.org/10.1039/d1ra06267k |
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