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Multiparametric Material Functionality of Microtissue‐Based In Vitro Models as Alternatives to Animal Testing (Adv. Sci. 10/2022)

Microtissue Engineering In article number 2105319 by Elena Stengelin, Julian Thiele, and Sebastian Seiffert, following the 3R principles of Russell and Burch (refinement, reduction, and replacement of animal experiments), microtissue‐based in vitro model systems are discussed as potential alternativ...

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Detalles Bibliográficos
Autores principales: Stengelin, Elena, Thiele, Julian, Seiffert, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981445/
http://dx.doi.org/10.1002/advs.202270064
Descripción
Sumario:Microtissue Engineering In article number 2105319 by Elena Stengelin, Julian Thiele, and Sebastian Seiffert, following the 3R principles of Russell and Burch (refinement, reduction, and replacement of animal experiments), microtissue‐based in vitro model systems are discussed as potential alternatives to animal experiments. Emphasis is placed on 1) fabrication techniques, 2) relevant material types, and 3) multiparametric material functionality such as processability, adaptivity, biocompatibility, and stability/degradability. [Image: see text]