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Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery
Catheters integrated with microcoils for electromagnetic steering under the high, uniform magnetic field within magnetic resonance (MR) scanners (3–7 Tesla) have enabled an alternative approach for active catheter operations. Achieving larger ranges of tip motion for Lorentz force‐based steering hav...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981448/ https://www.ncbi.nlm.nih.gov/pubmed/35112810 http://dx.doi.org/10.1002/advs.202105352 |
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author | Phelan, Martin Francis Tiryaki, Mehmet Efe Lazovic, Jelena Gilbert, Hunter Sitti, Metin |
author_facet | Phelan, Martin Francis Tiryaki, Mehmet Efe Lazovic, Jelena Gilbert, Hunter Sitti, Metin |
author_sort | Phelan, Martin Francis |
collection | PubMed |
description | Catheters integrated with microcoils for electromagnetic steering under the high, uniform magnetic field within magnetic resonance (MR) scanners (3–7 Tesla) have enabled an alternative approach for active catheter operations. Achieving larger ranges of tip motion for Lorentz force‐based steering have previously been dependent on using high power coupled with active cooling, bulkier catheter designs, or introducing additional microcoil sets along the catheter. This work proposes an alternative approach using a heat‐mitigated design and actuation strategy for a magnetic resonance imaging (MRI)‐driven microcatheter. A quad‐configuration microcoil (QCM) design is introduced, allowing miniaturization of existing MRI‐driven, Lorentz force‐based catheters down to 1‐mm diameters with minimal power consumption (0.44 W). Heating concerns are experimentally validated using noninvasive MRI thermometry. The Cosserat model is implemented within an MR scanner and results demonstrate a desired tip range up to 110° with 4° error. The QCM is used to validate the proposed model and power‐optimized steering algorithm using an MRI‐compatible neurovascular phantom and ex vivo kidney tissue. The power‐optimized tip orientation controller conserves as much as 25% power regardless of the catheter's initial orientation. These results demonstrate the implementation of an MRI‐driven, electromagnetic catheter steering platform for minimally invasive surgical applications without the need for camera feedback or manual advancement via guidewires. The incorporation of such system in clinics using the proposed design and actuation strategy can further improve the safety and reliability of future MRI‐driven active catheter operations. |
format | Online Article Text |
id | pubmed-8981448 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-89814482022-04-11 Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery Phelan, Martin Francis Tiryaki, Mehmet Efe Lazovic, Jelena Gilbert, Hunter Sitti, Metin Adv Sci (Weinh) Research Articles Catheters integrated with microcoils for electromagnetic steering under the high, uniform magnetic field within magnetic resonance (MR) scanners (3–7 Tesla) have enabled an alternative approach for active catheter operations. Achieving larger ranges of tip motion for Lorentz force‐based steering have previously been dependent on using high power coupled with active cooling, bulkier catheter designs, or introducing additional microcoil sets along the catheter. This work proposes an alternative approach using a heat‐mitigated design and actuation strategy for a magnetic resonance imaging (MRI)‐driven microcatheter. A quad‐configuration microcoil (QCM) design is introduced, allowing miniaturization of existing MRI‐driven, Lorentz force‐based catheters down to 1‐mm diameters with minimal power consumption (0.44 W). Heating concerns are experimentally validated using noninvasive MRI thermometry. The Cosserat model is implemented within an MR scanner and results demonstrate a desired tip range up to 110° with 4° error. The QCM is used to validate the proposed model and power‐optimized steering algorithm using an MRI‐compatible neurovascular phantom and ex vivo kidney tissue. The power‐optimized tip orientation controller conserves as much as 25% power regardless of the catheter's initial orientation. These results demonstrate the implementation of an MRI‐driven, electromagnetic catheter steering platform for minimally invasive surgical applications without the need for camera feedback or manual advancement via guidewires. The incorporation of such system in clinics using the proposed design and actuation strategy can further improve the safety and reliability of future MRI‐driven active catheter operations. John Wiley and Sons Inc. 2022-02-03 /pmc/articles/PMC8981448/ /pubmed/35112810 http://dx.doi.org/10.1002/advs.202105352 Text en © 2022 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Phelan, Martin Francis Tiryaki, Mehmet Efe Lazovic, Jelena Gilbert, Hunter Sitti, Metin Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery |
title | Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery |
title_full | Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery |
title_fullStr | Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery |
title_full_unstemmed | Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery |
title_short | Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery |
title_sort | heat‐mitigated design and lorentz force‐based steering of an mri‐driven microcatheter toward minimally invasive surgery |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981448/ https://www.ncbi.nlm.nih.gov/pubmed/35112810 http://dx.doi.org/10.1002/advs.202105352 |
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