Cargando…

Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery

Catheters integrated with microcoils for electromagnetic steering under the high, uniform magnetic field within magnetic resonance (MR) scanners (3–7 Tesla) have enabled an alternative approach for active catheter operations. Achieving larger ranges of tip motion for Lorentz force‐based steering hav...

Descripción completa

Detalles Bibliográficos
Autores principales: Phelan, Martin Francis, Tiryaki, Mehmet Efe, Lazovic, Jelena, Gilbert, Hunter, Sitti, Metin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981448/
https://www.ncbi.nlm.nih.gov/pubmed/35112810
http://dx.doi.org/10.1002/advs.202105352
_version_ 1784681606738345984
author Phelan, Martin Francis
Tiryaki, Mehmet Efe
Lazovic, Jelena
Gilbert, Hunter
Sitti, Metin
author_facet Phelan, Martin Francis
Tiryaki, Mehmet Efe
Lazovic, Jelena
Gilbert, Hunter
Sitti, Metin
author_sort Phelan, Martin Francis
collection PubMed
description Catheters integrated with microcoils for electromagnetic steering under the high, uniform magnetic field within magnetic resonance (MR) scanners (3–7 Tesla) have enabled an alternative approach for active catheter operations. Achieving larger ranges of tip motion for Lorentz force‐based steering have previously been dependent on using high power coupled with active cooling, bulkier catheter designs, or introducing additional microcoil sets along the catheter. This work proposes an alternative approach using a heat‐mitigated design and actuation strategy for a magnetic resonance imaging (MRI)‐driven microcatheter. A quad‐configuration microcoil (QCM) design is introduced, allowing miniaturization of existing MRI‐driven, Lorentz force‐based catheters down to 1‐mm diameters with minimal power consumption (0.44 W). Heating concerns are experimentally validated using noninvasive MRI thermometry. The Cosserat model is implemented within an MR scanner and results demonstrate a desired tip range up to 110° with 4° error. The QCM is used to validate the proposed model and power‐optimized steering algorithm using an MRI‐compatible neurovascular phantom and ex vivo kidney tissue. The power‐optimized tip orientation controller conserves as much as 25% power regardless of the catheter's initial orientation. These results demonstrate the implementation of an MRI‐driven, electromagnetic catheter steering platform for minimally invasive surgical applications without the need for camera feedback or manual advancement via guidewires. The incorporation of such system in clinics using the proposed design and actuation strategy can further improve the safety and reliability of future MRI‐driven active catheter operations.
format Online
Article
Text
id pubmed-8981448
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-89814482022-04-11 Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery Phelan, Martin Francis Tiryaki, Mehmet Efe Lazovic, Jelena Gilbert, Hunter Sitti, Metin Adv Sci (Weinh) Research Articles Catheters integrated with microcoils for electromagnetic steering under the high, uniform magnetic field within magnetic resonance (MR) scanners (3–7 Tesla) have enabled an alternative approach for active catheter operations. Achieving larger ranges of tip motion for Lorentz force‐based steering have previously been dependent on using high power coupled with active cooling, bulkier catheter designs, or introducing additional microcoil sets along the catheter. This work proposes an alternative approach using a heat‐mitigated design and actuation strategy for a magnetic resonance imaging (MRI)‐driven microcatheter. A quad‐configuration microcoil (QCM) design is introduced, allowing miniaturization of existing MRI‐driven, Lorentz force‐based catheters down to 1‐mm diameters with minimal power consumption (0.44 W). Heating concerns are experimentally validated using noninvasive MRI thermometry. The Cosserat model is implemented within an MR scanner and results demonstrate a desired tip range up to 110° with 4° error. The QCM is used to validate the proposed model and power‐optimized steering algorithm using an MRI‐compatible neurovascular phantom and ex vivo kidney tissue. The power‐optimized tip orientation controller conserves as much as 25% power regardless of the catheter's initial orientation. These results demonstrate the implementation of an MRI‐driven, electromagnetic catheter steering platform for minimally invasive surgical applications without the need for camera feedback or manual advancement via guidewires. The incorporation of such system in clinics using the proposed design and actuation strategy can further improve the safety and reliability of future MRI‐driven active catheter operations. John Wiley and Sons Inc. 2022-02-03 /pmc/articles/PMC8981448/ /pubmed/35112810 http://dx.doi.org/10.1002/advs.202105352 Text en © 2022 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Phelan, Martin Francis
Tiryaki, Mehmet Efe
Lazovic, Jelena
Gilbert, Hunter
Sitti, Metin
Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery
title Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery
title_full Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery
title_fullStr Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery
title_full_unstemmed Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery
title_short Heat‐Mitigated Design and Lorentz Force‐Based Steering of an MRI‐Driven Microcatheter toward Minimally Invasive Surgery
title_sort heat‐mitigated design and lorentz force‐based steering of an mri‐driven microcatheter toward minimally invasive surgery
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981448/
https://www.ncbi.nlm.nih.gov/pubmed/35112810
http://dx.doi.org/10.1002/advs.202105352
work_keys_str_mv AT phelanmartinfrancis heatmitigateddesignandlorentzforcebasedsteeringofanmridrivenmicrocathetertowardminimallyinvasivesurgery
AT tiryakimehmetefe heatmitigateddesignandlorentzforcebasedsteeringofanmridrivenmicrocathetertowardminimallyinvasivesurgery
AT lazovicjelena heatmitigateddesignandlorentzforcebasedsteeringofanmridrivenmicrocathetertowardminimallyinvasivesurgery
AT gilberthunter heatmitigateddesignandlorentzforcebasedsteeringofanmridrivenmicrocathetertowardminimallyinvasivesurgery
AT sittimetin heatmitigateddesignandlorentzforcebasedsteeringofanmridrivenmicrocathetertowardminimallyinvasivesurgery