Antiurease screening of alkyl chain-linked thiourea derivatives: in vitro biological activities, molecular docking, and dynamic simulations studies

Urease has become an important therapeutic target because it stimulates the pathogenesis of many human health conditions, such as pyelonephritis, the development of urolithiasis, hepatic encephalopathy, peptic ulcers, gastritis and gastric cancer. A series of alkyl chain-linked thiourea derivatives...

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Detalles Bibliográficos
Autores principales: Yaqoob, Sana, Hameed, Abdul, Ahmed, Mahmood, Imran, Muhammad, Qadir, Muhammad Abdul, Ramzan, Mahwish, Yousaf, Numan, Iqbal, Jamshed, Muddassar, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981555/
https://www.ncbi.nlm.nih.gov/pubmed/35424581
http://dx.doi.org/10.1039/d1ra08694d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981555/
https://www.ncbi.nlm.nih.gov/pubmed/35424581
http://dx.doi.org/10.1039/d1ra08694d

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