Thiazolidinedione derivatives as novel GPR120 agonists for the treatment of type 2 diabetes

GPR120, also called FFAR4, is preferentially expressed in the intestines, and can be stimulated by long-chain free fatty acids to increase the secretion of glucagon-like peptide-1 (GLP-1) from intestinal endocrine cells. It is known that GLP-1, as an incretin, can promote the insulin secretion from...

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Detalles Bibliográficos
Autores principales: Wang, Xuekun, Ji, Guoxia, Han, Xinyu, Hao, Huiran, Liu, Wenjing, Xue, Qidi, Guo, Qinghua, Wang, Shiben, Lei, Kang, Liu, Yadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981563/
https://www.ncbi.nlm.nih.gov/pubmed/35424534
http://dx.doi.org/10.1039/d1ra08925k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981563/
https://www.ncbi.nlm.nih.gov/pubmed/35424534
http://dx.doi.org/10.1039/d1ra08925k

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