A molecular approach integrating genomic and DNA methylation profiling for tissue of origin identification in lung-specific cancer of unknown primary

BACKGROUND: Determining the tissue of origin (TOO) is essential for managing cancer of unknown primary (CUP). In this study, we evaluated the concordance between genome profiling and DNA methylation analysis in determining TOO for lung-specific CUP and assessed their performance by comparing the cli...

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Detalles Bibliográficos
Autores principales: Chen, Kaiyan, Zhang, Fanrong, Yu, Xiaoqing, Huang, Zhiyu, Gong, Lei, Xu, Yanjun, Li, Hui, Yu, Sizhe, Fan, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981640/
https://www.ncbi.nlm.nih.gov/pubmed/35382836
http://dx.doi.org/10.1186/s12967-022-03362-2

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