NMR analysis of the enantiomeric purity of chiral diols by a new chiral boron agent

A new boric agent with bridged structure, boric acid D, was first synthesized and used as an excellent chiral derivative agent for highly efficient enantiodiscrimination of various diols. The derivatization reaction is fast and complete, easy to operate and has high accuracy in measurement of ee val...

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Detalles Bibliográficos
Autores principales: Zhang, Xuebo, Xu, Jing, Sun, Zhaofeng, Bian, Guangling, Song, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981704/
https://www.ncbi.nlm.nih.gov/pubmed/35425523
http://dx.doi.org/10.1039/d2ra00428c
Descripción
Sumario:A new boric agent with bridged structure, boric acid D, was first synthesized and used as an excellent chiral derivative agent for highly efficient enantiodiscrimination of various diols. The derivatization reaction is fast and complete, easy to operate and has high accuracy in measurement of ee values. The characteristic split NMR signals are well-distinguishable with a large chemical shift nonequivalence (up to 0.39 ppm).

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