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Zika virus vertical transmission in interferon receptor1-antagonized Rag1(−/−) mice results in postnatal brain abnormalities and clinical disease

The mechanisms by which vertically transmitted Zika virus (ZIKV) causes postnatal brain development abnormalities and congenital disease remain poorly understood. Here, we optimized the established anti-IFNAR1 treated, Rag1(−/−) (AIR) mouse model of ZIKV infection to examine the consequence of verti...

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Detalles Bibliográficos
Autores principales:	Winkler, Clayton W., Clancy, Chad S., Rosenke, Rebecca, Peterson, Karin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981715/ https://www.ncbi.nlm.nih.gov/pubmed/35379362 http://dx.doi.org/10.1186/s40478-022-01351-6

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