DEPDC1B Promotes Melanoma Angiogenesis and Metastasis through Sequestration of Ubiquitin Ligase CDC16 to Stabilize Secreted SCUBE3

The ability of melanoma to acquire metastasis through the induction of angiogenesis is one of the major causes of skin cancer death. Here, it is found that high transcript levels of DEP domain containing 1B (DEPDC1B) in cutaneous melanomas are significantly associated with a poor prognosis. Tissue m...

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Detalles Bibliográficos
Autores principales: Hu, Feng, Fong, Ki On, Cheung, May Pui Lai, Liu, Jessica Aijia, Liang, Rui, Li, Tsz Wai, Sharma, Rakesh, IP, Philip Pun‐Ching, Yang, Xintao, Cheung, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981904/
https://www.ncbi.nlm.nih.gov/pubmed/35088579
http://dx.doi.org/10.1002/advs.202105226

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