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Synthesis of novel series of 3,5-disubstituted imidazo[1,2-d] [1,2,4]thiadiazoles involving S(N)Ar and Suzuki–Miyaura cross-coupling reactions
The first access to 3,5-disubstituted imidazo[1,2-d][1,2,4]thiadiazole derivatives is reported. The series were generated from 2-mercaptoimidazole, which afforded the key intermediate bearing two functional positions. The S(N)Ar reactivity toward tosyl release at the C-3 position was investigated an...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981913/ https://www.ncbi.nlm.nih.gov/pubmed/35424561 http://dx.doi.org/10.1039/d1ra07208k |