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Emergence of Resistant Escherichia coli Mutants in Microfluidic On-Chip Antibiotic Gradients
Spatiotemporal structures and heterogeneities are common in natural habitats, yet their role in the evolution of antibiotic resistance is still to be uncovered. We applied a microfluidic gradient generator device to study the emergence of resistant bacteria in spatial ciprofloxacin gradients. We obs...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981919/ https://www.ncbi.nlm.nih.gov/pubmed/35391738 http://dx.doi.org/10.3389/fmicb.2022.820738 |