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RORγt phosphorylation protects against T cell-mediated inflammation

RAR-related orphan receptor-γ (RORγt) is an essential transcription factor for thymic T cell development, secondary lymphoid tissue organogenesis, and peripheral immune cell differentiation. Serine 182 phosphorylation is a major post-translational modification (PTM) on RORγt. However, the in vivo co...

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Detalles Bibliográficos
Autores principales:	Ma, Shengyun, Patel, Shefali A., Abe, Yohei, Chen, Nicholas, Patel, Parth R., Cho, Benjamin S., Abbasi, Nazia, Zeng, Suling, Schnabl, Bernd, Chang, John T., Huang, Wendy Jia Men
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982147/ https://www.ncbi.nlm.nih.gov/pubmed/35294872 http://dx.doi.org/10.1016/j.celrep.2022.110520

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