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The CXCR1/CXCR2 Inhibitor Reparixin Alters the Development of Myelofibrosis in the Gata1 (low) Mice

A major role for human (h)CXCL8 (interleukin-8) in the pathobiology of myelofibrosis (MF) has been suggested by observations indicating that MF megakaryocytes express increased levels of hCXCL8 and that plasma levels of this cytokine in MF patients are predictive of poor patient outcomes. Here, we d...

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Detalles Bibliográficos
Autores principales:	Verachi, Paola, Gobbo, Francesca, Martelli, Fabrizio, Martinelli, Andrea, Sarli, Giuseppe, Dunbar, Andrew, Levine, Ross L., Hoffman, Ronald, Massucci, Maria Teresa, Brandolini, Laura, Giorgio, Cristina, Allegretti, Marcello, Migliaccio, Anna Rita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982152/ https://www.ncbi.nlm.nih.gov/pubmed/35392239 http://dx.doi.org/10.3389/fonc.2022.853484

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