Iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines

An efficient iodine-mediated oxythiolation of o-vinylanilides with disulfides was developed. By virtue of this method, a series of thio-tethered benzoxazine derivatives were synthesized in good to excellent yields. The reaction features high yields, is metal-free, and has a wide substrate scope.

Detalles Bibliográficos
Autores principales: Yang, Yu, Liu, Liyan, Li, Kuiliang, Zha, Zhenggen, Sun, Qi, Wang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982212/
https://www.ncbi.nlm.nih.gov/pubmed/35424675
http://dx.doi.org/10.1039/d2ra01078j
Descripción
Sumario:An efficient iodine-mediated oxythiolation of o-vinylanilides with disulfides was developed. By virtue of this method, a series of thio-tethered benzoxazine derivatives were synthesized in good to excellent yields. The reaction features high yields, is metal-free, and has a wide substrate scope.

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