Iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines

An efficient iodine-mediated oxythiolation of o-vinylanilides with disulfides was developed. By virtue of this method, a series of thio-tethered benzoxazine derivatives were synthesized in good to excellent yields. The reaction features high yields, is metal-free, and has a wide substrate scope.

Detalles Bibliográficos
Autores principales: Yang, Yu, Liu, Liyan, Li, Kuiliang, Zha, Zhenggen, Sun, Qi, Wang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982212/
https://www.ncbi.nlm.nih.gov/pubmed/35424675
http://dx.doi.org/10.1039/d2ra01078j
_version_ 1784681759692029952
author Yang, Yu
Liu, Liyan
Li, Kuiliang
Zha, Zhenggen
Sun, Qi
Wang, Zhiyong
author_facet Yang, Yu
Liu, Liyan
Li, Kuiliang
Zha, Zhenggen
Sun, Qi
Wang, Zhiyong
author_sort Yang, Yu
collection PubMed
description An efficient iodine-mediated oxythiolation of o-vinylanilides with disulfides was developed. By virtue of this method, a series of thio-tethered benzoxazine derivatives were synthesized in good to excellent yields. The reaction features high yields, is metal-free, and has a wide substrate scope.
format Online
Article
Text
id pubmed-8982212
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-89822122022-04-13 Iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines Yang, Yu Liu, Liyan Li, Kuiliang Zha, Zhenggen Sun, Qi Wang, Zhiyong RSC Adv Chemistry An efficient iodine-mediated oxythiolation of o-vinylanilides with disulfides was developed. By virtue of this method, a series of thio-tethered benzoxazine derivatives were synthesized in good to excellent yields. The reaction features high yields, is metal-free, and has a wide substrate scope. The Royal Society of Chemistry 2022-03-04 /pmc/articles/PMC8982212/ /pubmed/35424675 http://dx.doi.org/10.1039/d2ra01078j Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Yang, Yu
Liu, Liyan
Li, Kuiliang
Zha, Zhenggen
Sun, Qi
Wang, Zhiyong
Iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines
title Iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines
title_full Iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines
title_fullStr Iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines
title_full_unstemmed Iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines
title_short Iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines
title_sort iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982212/
https://www.ncbi.nlm.nih.gov/pubmed/35424675
http://dx.doi.org/10.1039/d2ra01078j
work_keys_str_mv AT yangyu iodinemediatedoxythiolationofovinylanilideswithdisulfidesforthesynthesisofbenzoxazines
AT liuliyan iodinemediatedoxythiolationofovinylanilideswithdisulfidesforthesynthesisofbenzoxazines
AT likuiliang iodinemediatedoxythiolationofovinylanilideswithdisulfidesforthesynthesisofbenzoxazines
AT zhazhenggen iodinemediatedoxythiolationofovinylanilideswithdisulfidesforthesynthesisofbenzoxazines
AT sunqi iodinemediatedoxythiolationofovinylanilideswithdisulfidesforthesynthesisofbenzoxazines
AT wangzhiyong iodinemediatedoxythiolationofovinylanilideswithdisulfidesforthesynthesisofbenzoxazines

Ejemplares similares