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Nintedanib and Dasatinib Treatments Induce Protective Autophagy as a Potential Resistance Mechanism in MPM Cells

Malignant pleural mesothelioma (MPM) is a rare type of cancer with a grim prognosis. So far, no targetable oncogenic mutation was identified in MPM and biomarkers with predictive value toward drug sensitivity or resistance are also lacking. Nintedanib (BIBF1120) is a small-molecule tyrosine kinase i...

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Detalles Bibliográficos
Autores principales:	Hegedüs, Luca, Szücs, Kata D., Kudla, Matthias, Heidenreich, Julian, Jendrossek, Verena, Peña-Llopis, Samuel, Garay, Tamas, Czirok, Andras, Aigner, Clemens, Plönes, Till, Vega-Rubin-de-Celis, Silvia, Hegedüs, Balazs
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982261/ https://www.ncbi.nlm.nih.gov/pubmed/35392170 http://dx.doi.org/10.3389/fcell.2022.852812

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