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Development of a mobile low-field MRI scanner

Magnetic resonance imaging (MRI) allows important visualization of the brain and central nervous system anatomy and organization. However, unlike electroencephalography (EEG) or functional near infrared spectroscopy, which can be brought to a patient or study participant, MRI remains a hospital or c...

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Autores principales: Deoni, Sean C. L., Medeiros, Paul, Deoni, Alexandra T., Burton, Phoebe, Beauchemin, Jennifer, D’Sa, Viren, Boskamp, Eddy, By, Samantha, McNulty, Chris, Mileski, William, Welch, Brian E., Huentelman, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982311/
https://www.ncbi.nlm.nih.gov/pubmed/35383255
http://dx.doi.org/10.1038/s41598-022-09760-2
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author Deoni, Sean C. L.
Medeiros, Paul
Deoni, Alexandra T.
Burton, Phoebe
Beauchemin, Jennifer
D’Sa, Viren
Boskamp, Eddy
By, Samantha
McNulty, Chris
Mileski, William
Welch, Brian E.
Huentelman, Matthew
author_facet Deoni, Sean C. L.
Medeiros, Paul
Deoni, Alexandra T.
Burton, Phoebe
Beauchemin, Jennifer
D’Sa, Viren
Boskamp, Eddy
By, Samantha
McNulty, Chris
Mileski, William
Welch, Brian E.
Huentelman, Matthew
author_sort Deoni, Sean C. L.
collection PubMed
description Magnetic resonance imaging (MRI) allows important visualization of the brain and central nervous system anatomy and organization. However, unlike electroencephalography (EEG) or functional near infrared spectroscopy, which can be brought to a patient or study participant, MRI remains a hospital or center-based modality. Low magnetic field strength MRI systems, however, offer the potential to extend beyond these traditional hospital and imaging center boundaries. Here we describe the development of a modified cargo van that incorporates a removable low-field permanent magnet MRI system and demonstrate its proof-of-concept. Using phantom scans and in vivo T(2)-weighted neuroimaging data, we show no significant differences with respect to geometric distortion, signal-to-noise ratio, or tissue segmentation outcomes in data acquired in the mobile system compared to a similar static system in a laboratory setting. These encouraging results show, for the first time, MRI that can be performed at a participant’s home, community center, school, etc. Breaking traditional barriers of access, this mobile approach may enable imaging of patients and participants who have mobility challenges, live long distances from imaging centers, or are otherwise unable to travel to an imaging center or hospital.
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spelling pubmed-89823112022-04-06 Development of a mobile low-field MRI scanner Deoni, Sean C. L. Medeiros, Paul Deoni, Alexandra T. Burton, Phoebe Beauchemin, Jennifer D’Sa, Viren Boskamp, Eddy By, Samantha McNulty, Chris Mileski, William Welch, Brian E. Huentelman, Matthew Sci Rep Article Magnetic resonance imaging (MRI) allows important visualization of the brain and central nervous system anatomy and organization. However, unlike electroencephalography (EEG) or functional near infrared spectroscopy, which can be brought to a patient or study participant, MRI remains a hospital or center-based modality. Low magnetic field strength MRI systems, however, offer the potential to extend beyond these traditional hospital and imaging center boundaries. Here we describe the development of a modified cargo van that incorporates a removable low-field permanent magnet MRI system and demonstrate its proof-of-concept. Using phantom scans and in vivo T(2)-weighted neuroimaging data, we show no significant differences with respect to geometric distortion, signal-to-noise ratio, or tissue segmentation outcomes in data acquired in the mobile system compared to a similar static system in a laboratory setting. These encouraging results show, for the first time, MRI that can be performed at a participant’s home, community center, school, etc. Breaking traditional barriers of access, this mobile approach may enable imaging of patients and participants who have mobility challenges, live long distances from imaging centers, or are otherwise unable to travel to an imaging center or hospital. Nature Publishing Group UK 2022-04-05 /pmc/articles/PMC8982311/ /pubmed/35383255 http://dx.doi.org/10.1038/s41598-022-09760-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Deoni, Sean C. L.
Medeiros, Paul
Deoni, Alexandra T.
Burton, Phoebe
Beauchemin, Jennifer
D’Sa, Viren
Boskamp, Eddy
By, Samantha
McNulty, Chris
Mileski, William
Welch, Brian E.
Huentelman, Matthew
Development of a mobile low-field MRI scanner
title Development of a mobile low-field MRI scanner
title_full Development of a mobile low-field MRI scanner
title_fullStr Development of a mobile low-field MRI scanner
title_full_unstemmed Development of a mobile low-field MRI scanner
title_short Development of a mobile low-field MRI scanner
title_sort development of a mobile low-field mri scanner
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982311/
https://www.ncbi.nlm.nih.gov/pubmed/35383255
http://dx.doi.org/10.1038/s41598-022-09760-2
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