Synthesis of C-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents

An efficient and versatile synthesis of the naturally occurring C-prenylated stilbenoid methyl ethers and their synthetic analogues is presented. The synthesis represents a six step convergent process including an optimised C-prenylation method. Furthermore, during the demethylation process, six new...

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Detalles Bibliográficos
Autores principales: Pizova, Hana, Malanik, Milan, Smejkal, Karel, Oravec, Michal, Bobal, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982364/
https://www.ncbi.nlm.nih.gov/pubmed/35424730
http://dx.doi.org/10.1039/d2ra00441k
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author Pizova, Hana
Malanik, Milan
Smejkal, Karel
Oravec, Michal
Bobal, Pavel
author_facet Pizova, Hana
Malanik, Milan
Smejkal, Karel
Oravec, Michal
Bobal, Pavel
author_sort Pizova, Hana
collection PubMed
description An efficient and versatile synthesis of the naturally occurring C-prenylated stilbenoid methyl ethers and their synthetic analogues is presented. The synthesis represents a six step convergent process including an optimised C-prenylation method. Furthermore, during the demethylation process, six new dihydro-benzopyranyl derivatives were obtained and isolated.
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spelling pubmed-89823642022-04-13 Synthesis of C-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents Pizova, Hana Malanik, Milan Smejkal, Karel Oravec, Michal Bobal, Pavel RSC Adv Chemistry An efficient and versatile synthesis of the naturally occurring C-prenylated stilbenoid methyl ethers and their synthetic analogues is presented. The synthesis represents a six step convergent process including an optimised C-prenylation method. Furthermore, during the demethylation process, six new dihydro-benzopyranyl derivatives were obtained and isolated. The Royal Society of Chemistry 2022-03-15 /pmc/articles/PMC8982364/ /pubmed/35424730 http://dx.doi.org/10.1039/d2ra00441k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Pizova, Hana
Malanik, Milan
Smejkal, Karel
Oravec, Michal
Bobal, Pavel
Synthesis of C-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents
title Synthesis of C-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents
title_full Synthesis of C-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents
title_fullStr Synthesis of C-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents
title_full_unstemmed Synthesis of C-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents
title_short Synthesis of C-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents
title_sort synthesis of c-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982364/
https://www.ncbi.nlm.nih.gov/pubmed/35424730
http://dx.doi.org/10.1039/d2ra00441k
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