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Surrogacy Beyond Prognosis: The Importance of “Trial-Level” Surrogacy
Many candidate surrogate endpoints are currently assessed using a 2-level statistical approach, which consists in checking whether (1) the potential surrogate is associated with the final endpoint in individual patients and (2) the effect of treatment on the surrogate can be used to reliably predict...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982389/ https://www.ncbi.nlm.nih.gov/pubmed/35380717 http://dx.doi.org/10.1093/oncolo/oyac006 |