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OBIF: an omics-based interaction framework to reveal molecular drivers of synergy

Bioactive molecule library screening may empirically identify effective combination therapies, but molecular mechanisms underlying favorable drug–drug interactions often remain unclear, precluding further rational design. In the absence of an accepted systems theory to interrogate synergistic respon...

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Detalles Bibliográficos
Autores principales:	Pantaleón García, Jezreel, Kulkarni, Vikram V, Reese, Tanner C, Wali, Shradha, Wase, Saima J, Zhang, Jiexin, Singh, Ratnakar, Caetano, Mauricio S, Kadara, Humam, Moghaddam, Seyed Javad, Johnson, Faye M, Wang, Jing, Wang, Yongxing, Evans, Scott E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Methods Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982434/ https://www.ncbi.nlm.nih.gov/pubmed/35387383 http://dx.doi.org/10.1093/nargab/lqac028

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